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Anti-CHIKV Spike glycoprotein E2 Antibody (CHK265) (VK572013)

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Overview
Catalog No.VK572013
Species reactivityChikungunya virus (strain S27-African prototype) (CHIKV), Mayaro virus(MAYV), Ross River Virus (RRV), O'nyong'nyong virus (ONNV), Semliki Forest virus (SFV)
ApplicationsELISA, FCM, Neutralization
Host speciesHuman
IsotypeIgG1, kappa
Clone IDCHK265
ClonalityMonoclonal
TargetStructural polyprotein, Envelope glycoprotein E2, Spike glycoprotein E2
Endotoxin levelPlease contact with the lab for this information.
Purity>95% as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
AccessionQ8JUX5
FormLiquid
Storage buffer0.01M PBS, pH 7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
BackgroundChikungunya virus (CHIKV) is an arthropod-borne alphavirus that causes Chikungunya fever, a re-emerging disease characterized by high fever, rash, and arthralgia. The E2 envelope glycoprotein is a structural protein that forms heterodimers with the E1 glycoprotein and is displayed on the viral surface as part of trimeric spike complexes. E2 is primarily responsible for receptor binding and host cell attachment, playing a key role in viral entry. As a major target of neutralizing antibodies, the E2 protein is widely used in serological diagnostics, vaccine development, and antiviral research.
NoteFor research use only.
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