Neutralizing vs. binding antibodies—what’s the difference?

Neutralizing antibodies block infection (entry/fusion) and show functional activity (PRNT/pseudovirus), whereas binding antibodies may not block infection.

PRNT vs. pseudovirus vs. sVNT—how should I choose?

PRNT uses infectious virus (gold standard); pseudovirus enables BSL-2 functional readouts; sVNT screens receptor blocking on plates for fast throughput.

How do I interpret IC50/ID50 values?

Lower IC50/ID50 denotes stronger neutralization under matched conditions; compare across the same assay setup only.

All antibodies are for Research Use Only (RUO) and not for diagnostic or therapeutic use.

Neutralizing Antibodies

Discover neutralizing antibodies for functional blocking, viral neutralization, and pathway inhibition. Validated in cell-based bioassays with confirmed IC₅₀/EC₅₀ values. RUO

Why Researchers Choose abinScience

Application-Validated Rigorously tested for WB, IHC, IF, ELISA, and FC with supporting images and data on every product page.

High Specificity & Sensitivity Monoclonal and polyclonal options with validated target specificity, minimal cross-reactivity, and lot-specific titer data.

Broad Species Reactivity Covering human, mouse, rat, and additional species for translational and comparative research.

Multiple Conjugation Options Unconjugated, HRP, AP, biotin, FITC, PE, APC, and other fluorochrome conjugates ready for your workflow.

Original Manufacturer Quality In-house development from immunogen design to final QC — full traceability and batch consistency guaranteed.

How to Select the Right Product

Target & Species : PRNT/pseudovirus for functional titers (IC50/ID50); sVNT for rapid screening. Compare IC50 across matched assay conditions.
Application : Select antibodies validated for your specific assay — WB, IHC (paraffin/frozen), IF, ELISA, or flow cytometry (FC).
Clonality: Monoclonal for reproducibility and epitope specificity; polyclonal for broader epitope recognition and enhanced signal in WB/IHC.
Conjugation : Choose unconjugated for maximum flexibility, or HRP/fluorochrome conjugates for direct detection without secondary antibodies.

Documents & QC Data

Download product datasheets, validation images (WB/IHC/IF/FC), CoA, and application protocols on each product page. All data is lot-specific.

FAQs

How are your antibodies validated?

Every antibody is validated in its listed applications (WB, IHC, IF, ELISA, FC) with supporting images and data on the product page. We use positive and negative controls plus knockout/knockdown verification where available.

Do you offer conjugated antibodies?

Yes — HRP, AP, biotin, FITC, PE, APC, Alexa Fluor, and other fluorochrome conjugates are available. Custom conjugation services are also offered for bulk orders.

What species do your antibodies react with?

Most antibodies target human, mouse, and rat. Many show validated cross-reactivity with additional species. Check the product datasheet for confirmed reactivity data.

What is your replacement policy?

If a product does not perform as described under recommended conditions, contact us within 30 days for replacement or credit. Our technical team will help troubleshoot first.

Can I get custom antibodies?

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Product types

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Antibodies (726)
Expression system

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Mammalian Cells (4)

Mammalian (1)
Target

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GDF2/BMP9 (1)

GIPR/GIP-R (1)

EDE1 (1)

TSHR/LGR3 (2)

CD49d/ITGA4 (1)

L3/CP-H/Protein II (1)

Spike glycoprotein E1 (2)

A27L (5)

Outer capsid glycoprotein VP7 (1)

Capsid protein VP1 (2)

env/Envelope protein (1)

Hepacivirin/NS3P/Viroporin p70 (3)

THPO/Thrombopoietin (1)

Galectin-3/Gal-3 (1)

CD295/LEPR (1)

CNR1/CB1 (3)

CDH17/Cadherin-17 (1)

L2/Minor capsid protein L2 (2)

Spike glycoprotein 2 (5)

BMP6 (1)

VSIG4/CRIg (1)

CD205/LY75/DEC-205 (1)

VTCN1/B7-H4 (1)

Tityustoxin VII/Toxin VII/Ts7 (1)

GPC3/Glypican 3 (1)

SOD1 (1)

PTP4A1/PRL1 (1)

WNT2 (4)

CXCL12/SDF-1 (1)

CD198/CCR8 (4)

Protein prM/prM (3)

tetX/Tetanus toxin (1)

Fusion glycoprotein/F Trimer (1)

IL36RN/IL-1F5/IL-36Ra (1)

VEGFA (1)

GREM1/DAND2 (1)

CD37/TSPAN26 (2)

MSTN/GDF8 (1)

fimH (1)

TGFB1 (2)

GP1 glycoprotein (2)

CD8a/Lyt2 (3)

Capsid protein VP2 (2)

IL22 (1)

stxB/SLT-1b/VT1 (2)

SLC39A6/LIV-1 (1)

IL20 (1)

CCL3/MIP-1-alpha (1)

TGFB2/TGF-beta-2 (1)

Spike glycoprotein (1)

pfo/Perfringolysin O/Theta-toxin (3)

HA/Hemagglutinin (2)

Capsid (1)

CD307e/FCRL5 (1)

LRRC15/LIB (1)

Beta-toxin Cl13/Cb3 (3)

gp120/Glycoprotein 120 (1)

CD84 (1)

TNFSF15/TL1A (1)

ALPP/PLAP (1)

BMP4 (1)

gH/gL Complexes (2)

CXCL11/I-TAC (1)

CCL1/I-309 (1)

TSLP (1)

CA9 (1)

G/Major surface glycoprotein G (2)

Dupilumab (2)

FOLH1/PSMA (1)

OPN/SPP1 (1)

RBD (Omicron/KP.2) (2)

Hemagglutinin/HA (1)

F12/Coagulationfactor XII (1)

gp32/gp35/Envelope glycoprotein E1 (1)

CSF3/G-CSF (1)

InlB/Internalin B (1)

Outer capsid protein VP4 (1)

gp125 (1)

Glycoprotein C/Gc (4)

gH/UL75 (1)

H3L/Ag35 (2)

IL2 (1)

Structural polyprotein (1)

F/fusion protein (2)

p67 (1)

IL18/IL1F4 (1)

PTP4A3/PRL3 (1)

IL1A/IL1F1 (1)

IFNAR1 (1)

L1R/Protein L1 (4)

EGFRvIII-specific/EGFR variant III (2)

FGF21 (1)

CTGF/CCN2 (1)

IL1B/IL1F2 (1)

Capsid protein VP25 (2)

Procapsid [(VP0/1/3) 5] 12 (2)

RBP2b (1)

CXCL1/NAP-3/GRO-alpha (1)

ROR1/NTRKR1 (1)

sLea/CA19-9 (1)

wlaB/pglK (1)

CCL2/MCP-1 (1)

CD16/CD32 (1)

IL23A (1)

CCL8/MCP-2 (1)

TGFA/TGF-alpha (1)

VWF (1)

ACE2 (3)

RBD (23)

CXCL2/GRO-beta/MIP2-alpha (1)

A29L (2)

EGFL7 (1)

Capsid protein (13)

ProteinUL128 & UL131A (1)

VP1/Coatprotein VP1 (2)

Envelope glycoprotein GP350 (1)

APCS/PTX2 (1)

PSCA (1)

gH/Envelope glycoprotein H (1)

GP/Envelopment polyprotein (1)

HHRF3/US28 (1)

IFNB1/IFN-beta (1)

CD254/RANKL/TNFSF11 (1)

NS1/gp68/gp70 (40)

mature virion in complex (5)

Genome polyprotein (5)

CD132/IL2RG (1)

RSPO3 (1)

M1R (4)

ARG1/Arginase-1 (2)

NS1/Non-structural protein 1 (1)

GP/Glycoprotein (5)

Capsid protein VP 1/2/3 (2)

botA/BOTOX (1)

SNCA/Alpha-synuclein (5)

GP1 (2)

PA/pagA/PA-83 (2)

GPRC5D (1)

CD227/MUC1 (1)

IL5 (1)

Toxin A/tcdA (2)

Fc Block (1)

ANGPTL3 (1)

GPC (18)

Fusion glycoprotein F0 (5)

Protein P (1)

Neuraminidase/NA (4)

RBD (Omicron/JN.1) (2)

STEAP1 (1)

E6/Protein E6 (1)

CXCL10/IP-10 (1)

ENT2/SLC29A2 (1)

CX3CL1/Fractalkine (1)

Glycoprotein G (17)

ssRNA & Genome polyprotein (2)

PTHrP/PTHLH(1-34) (1)

CD52 (1)

entB/SEB (1)

GFRAL (1)

ADM/Adrenomedullin (1)

L1/Major capsid protein L1 (2)

CD137/4-1BB (2)

NLRP3 (1)

RAGE/AGER (1)

ADAMTS5 (2)

env/Envpolyprotein (1)

CCL24/Eotaxin-2/MPIF-2 (1)

Rabbit hemorrhagic disease virus (RHDV) Capsid protein (1)

CD16/FCGR3 (1)

IL17F (1)

HBEGF (1)

gB/UL27 (1)

IFNA1/Interferon alpha-D (1)

CCL11/Eotaxin (1)

CDH1/CDH11 (1)

long-chain neurotoxin (1)

D8L (2)

botA/BoNT (2)

gB/BALF4 (2)

aPC/Activated protein C (3)

PDGFD (1)

SplB (1)

CD172a/SIRPA (3)

LGR5/GPR49 (1)

env/Env polyprotein (4)

CD152/CTLA4 (4)

Major surface glycoprotein G (3)

Intermediate capsid protein VP6 (1)

ADAMTS4 (4)

F2/Prothrombin/PIVKA-II (1)

shiga toxin type 2A/stx2A (1)

ATTR/Transthyretin amyloidosis (5)

TNFa/TNF-alpha (1)

Neuropeptide Y/NPY (1)

shiga toxin type 2/stx2B (1)

FedF (1)

CD73/NT5E (2)

TSG101 (2)

E-DII (1)

RHDV VP60 (1)

FSHR (1)

Hemagglutinin (H7 subtype) (4)

Ly6g/Ly-6G.1 (2)

NGF/Beta-NGF (2)

CXCL4/PF4 (1)

F8/Coagulation factor VIII (4)

CDH11 (1)

CLDN3/Claudin-3 (1)

CD3 (1)

P domain (4)

CD96 (2)

LAMP5 (2)

PDGFB (1)

SFRP1 (1)

gp120 (2)

ACVRL1/ALK-1 (1)

IL38/IL1F10 (2)

gE/Envelope glycoprotein E (1)

CD319/SLAMF7 (1)

LTA/TNF-beta (1)

E1 & E2 (gp35 & gp70) (3)

TNFSF9/4-1BBL (2)

AFP/Alpha-fetoprotein (1)

IL17C (1)

BMP10 (1)

Pvs25 (1)

UL130 (1)

iga/IgA1 protease (1)

IGF2 (1)

VLP (1)

CSF1/M-CSF (1)

MUC16/CA-125 (1)

shiga toxin type 1B/stx1B (2)

GDF11/BMP11 (1)

CD274/PD-L1 (2)

BAG3 (1)

LRP6 (1)

ERVW-1/HERV-W-Env (1)

CD337/NCR3/NKp30 (1)

G9&A16 complex (2)

HGF (1)

NP/Nucleoprotein (3)

BDNF (1)

APOE (1)

protruding (P) domain (1)

Envelope protein E (13)

TREML1/TLT1 (1)

DKK1 (2)

CCL5/RANTES (1)

IL11RA (1)

STAT3 (1)

CD124/IL4RA (1)

PRLR (1)

TREM1 & CD46 (1)

IL17A (4)

RBD (S6P trimer) (3)

A33R (2)

CD222/IGF2R (1)

ROBO4 (1)

IL13 (1)

APP/Amyloid beta (1)

Mature virion in Complex [(VP0/1/3)5]12 (2)

CXCL13/BCA-1/BLC (1)

IL10 (1)

SSTR2/SRIF-1 (1)

CD20/MS4A1 (1)

gp46 (2)

IGF1 (1)

MSLN/Mesothelin (1)

IFN α2/IFNA2 (1)

CFD (1)

CD120b/TNFR2 (1)

FAP/FAPalpha (1)

p21/Mature core protein (1)

CD279/PD-1 (9)

S1 N-terminal domain/S1-NTD (3)

CD228/MELTF (1)

long-chain α-neurotoxins (1)

CD48 (1)

MUC5AC (1)

GPA33 (1)

Glycoprotein (1)

CD283/TLR3 (2)

H3L (2)

Heparanase (1)

DPEP3 (1)

C1S (1)

IL11 (1)

A35R (5)

S2 Protein (3)

EPO (1)

DT/Diphtheria toxin (3)

gp140/Env Trimer (2)

IL4 (1)

IFNG/IFN-gamma (2)

E8L (2)

CD127/IL7R (1)

F/Fusion glycoprotein F0 (16)

MERS-CoV RBD (1)

ARC (3)

CD100/SEMA4D (3)

CD21/CR2 (1)

Virionprotein 1/2/3 (1)

Spike (5)

CD335/NCR1/NKp46 (1)

IL31RA (1)

Capsid protein VP3 (1)

Toxin B/tcdB (2)

IL9 (1)

short-chain neurotoxin (1)

SERPINE1/PAI-1 (1)

ANGPTL4 (5)

IL21 (1)

CD309/VEGFR-2 (1)

E2s (2)

CCL14/NCC-2 (1)

Pre-F/Fusion glycoprotein F0 (2)

E7/Protein E7 (4)

CSF2/GM-CSF (1)

BMP2 (2)

CD122/IL2RB (1)

SAA (1)

Envelopeglycoprotein E2/gp55 (2)

gB/Envelope glycoprotein B (7)

Major capsid protein L1 (11)

gH/BXLF2 (2)

G/Glycoprotein (5)

lukF (1)

GDF15/MIC1 (1)

OSM/Oncostatin-M (1)

Spike glycoprotein E2 (1)

Flt3 ligand/FLT3LG (1)

gD/Envelope glycoprotein D (1)

ROBO2 (1)

KLKB1/KLK3 (1)

CD40/TNFRSF5 (1)

Alpha-toxin/hly (3)

BLLF1/MA/GP350 (1)

gB (2)

Alpha-cobratoxin (1)

pro-MSTN/GDF8 (1)

IL6 (1)

CD268/TNFRSF13C (2)

B6R (2)

IL8/CXCL8 (1)

PDGFC (1)

IL31 (4)

Virionprotein 1/VP1 (1)

Fusion glycoprotein (3)

CCL17/TARC (1)

EDB & CD3E (1)

S/Spike glycoprotein (2)

HSV- gB (1)

IL12B/IL-12 p40 (1)

CD62L/SELL (1)

CD226/DNAM-1 (1)

PODXL (2)

FCGRT/FCRN (1)

Fusion Protein (1)

CXCL9/MIG (1)

Gn (9)

Prefusion Protein (2)
Species

0 selected

Tai Forest ebolavirus (TAFV) (1)

Human hepatitis A virus (HHAV) (1)

Human papillomavirus 58 (HPV58) (3)

Staphylococcus aureus (3)

Monkey (1)

Human metapneumovirus (HMPV) (4)

Human adenovirus 3 (HAdV-3) (1)

Rotavirus A (RV-A) (3)

Poliovirus type 1 (PV1) (2)

Ebola virus (EBOV) (1)

Human papillomavirus 16 (HPV16) (2)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (22)

Brazilian scorpion (1)

Machupo virus (MACV) (1)

Dengue virus type 1 (DENV-1) (1)

Human immunodeficiency virus 1 (HIV-1) (9)

Varicella-zoster virus (VZV/HHV-3) (4)

Bovine respiratory syncytial virus (BRSV) (2)

Sudan ebolavirus (SEBOV) (1)

Human herpesvirus 1 (HSV-1/HHV-1) (3)

Human betacoronavirus 2c EMC/2012 (HCoV-EMC) (2)

Rotavirus (RV) (1)

Hantaan virus (HTNV) (2)

Hepatitis C Virus (HCV) (9)

Lassa virus (LASV) (1)

Dengue virus type 3 (DENV-3) (1)

Enterovirus 71 (EV71) (4)

Hendra virus (HeV) (2)

Campylobacter jejuni subsp. (1)

Middle East respiratory syndrome-related coronavirus (MERS-CoV) (5)

Orthohantavirus puumalaense (PUUV) (1)

Human cytomegalovirus (HCMV/HHV-5) (7)

Coxsackievirus A16 (CVA16) (2)

Puumala virus (PUUV) (2)

Human parvovirus B19 (HPV B19) (3)

Zaire ebolavirus (ZEBOV) (6)

Zika virus (ZIKV) (4)

Junin mammarenavirus (JUNV) (1)

Dengue virus type 4 (DENV-4) (1)

Nipah virus (NiV) (13)

Influenza A virus (Flu A) (5)

Dog (10)

Human papillomavirus 6 (HPV6) (1)

Coxsackievirus B1 (CBV1) (3)

Dobrava-Belgrade virus (DOBV) (2)

Suid alphaherpesvirus 1 (SuHV-1/PRV) (2)

Severe acute respiratory syndrome coronavirus (SARS-CoV) (3)

Clostridium botulinum (2)

Epstein-Barr virus (EBV/HHV-4) (2)

Rabbit (2)

Cat (1)

Seoul virus (SEOV) (2)

Rat (1)

E. coli (4)

Human respiratory syncytial virus (HRSV) (12)

Hepatitis E virus/HEV (1)

Andes virus (ANDV) (2)

Plasmodium vivax (2)

Streptococcus pneumoniae (1)

Chikungunya virus (CHIKV) (1)

Human papillomavirus 59 (HPV59) (1)

Human endogenous retroviruses W (HERV-W) (1)

Reston ebolavirus (REBOV) (1)

Dengue virus type 2 (DENV-2) (8)

Bundibugyo ebolavirus (BDBV) (1)

Sin Nombre virus (SNV) (2)

Japanese encephalitis virus (JEV) (1)

Human (177)

Mouse (33)

Porcine circovirus 2 (PCV2) (2)

Human astrovirus-8 (HAtVs) (1)

Human metapneumovirus (2)

Clostridioides difficile (2)
Applications

0 selected

Neutralization (705)

in vivo study (1)

FCM (121)

in vitro neutralization (1)

IF (22)

in vivo CTLA-4 neutralization (2)

IHC (18)

SPR (46)

in vivo neutralization (5)

in vivo (2)

in vivo intra-tumoral regulatory T cell depletion (2)

Antagonist (1)

NK cell activation (1)

Neutralizatio (1)

BLI (4)

WB (59)

Cell Isolation (1)

in vivo CD8+ T cell depletion (1)

Cell Depletion (1)

DB (3)

in vivo neutrophil depletion (2)

Western blot (1)

IP (9)

neutralizing (1)

FuncS (4)

RIA (1)

in vivo MDSC depletion (2)

IB (1)

Blocking (2)

ELISA (620)

Nneutralization (1)

in vivo research (1)

ICC (3)

in vivo protection (1)
Reactivity

0 selected

Human (57)

Bovine viral diarrhea virus (BVDV) (2)

Epstein-Barr virus (EBV/HHV-4) (3)

Human respiratory syncytial virus (HRSV) (5)

Chikungunya virus (CHIKV) (4)

Naja kaouthia (1)

Porcine circovirus 2 (PCV2) (1)

Dengue Virus type 4 (DENV-4) (1)

Monkeypox virus (5)

Severe acute respiratory syndrome coronavirus (SARS-CoV) (1)

HSV-1 (3)

Hendra virus (1)

severe fever with thrombocytopenia syndrome virus (SFTSV) (8)

Dengue virus (1)

Human coronavirus HKU1 (HCoV-HKU1) (1)

Crimean-Congo hemorrhagic fever virus (2)

Vaccinia virus (VACV) (20)

RD114 retrovirus (1)

Mayaro virus(MAYV) (1)

Clostridium tetani (1)

Monkey (1)

Escherichia coli (1)

Yellow Fever Virus (YFV) (1)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (5)

Influenza A virus (H7N1) (1)

HAstV-1 (2)

Bacteriophage H19B (2)

HSV-2 (3)

Clostridium perfringens (3)

Canine parvovirus (1)

Mexican scorpion (3)

Nipah virus (1)

Zika virus (1)

Vesicular stomatitis Indiana virus (VSIV) (2)

Ross River Virus (RRV) (2)

Venezuelan equine encephalitis virus (VEEV) (1)

Theileria parva (1)

Klebsiella pneumoniae (1)

Zika virus (ZIKV) (1)

Influenza A virus (H7N3) (2)

SARS-CoV (1)

Human astrovirus-8 (HAtVs) (1)

Norwalk virus (3)

Norwalk virus (NV) (5)

Influenza B virus (2)

Coxsackievirus A16 (CVA16) (3)

Listeria monocytogenes (1)

Foot-and-mouth disease virus (FMDV) (2)

Human papillomavirus 16 (HPV16) (13)

O'nyong'nyong virus (ONNV) (1)

Human enterovirus 71 (EV71) (3)

Clostridium botulinum (1)

Western equine encephalitis virus (WEEV) (1)

Measles virus (MeV) (2)

Japanese encephalitis virus (JEV) (2)

West Nile virus (WNV) (1)

Junin mammarenavirus (JUNV) (3)

Bacillus anthracis (2)

SARS-CoV-2 (1)

Clostridioides difficile (2)

Lassa virus (LASV) (16)

Parainfluenza virus 5 (PIV5) (1)

Epstein-Barr virus (HHV-4) (Human herpesvirus 4) (1)

Hendra virus (HeV) (12)

Puumala virus (1)

Semliki Forest virus (SFV) (1)

Eastern equine encephalitis virus (EEEV) (1)

Machupo virus (MACV) (1)

Influenza A virus (H7N9) (1)

HCoV-229E (2)

Hepatitis C Virus (HCV) (43)

IgG1b12 (1)

Nipah virus (NiV) (13)

Mouse (26)

Middle East respiratory syndrome-related coronavirus (MERS-CoV) (8)

Coxsackievirus B1 (CVB1) (3)

Dengue Virus type 1 (DENV-1) (1)

Scorpion (2)

Guertu Virus (GTV) (3)

Homo sapiens (Human) (1)

Influenza A virus H7 subtype (2)

O’nyong’nyong virus (ONNV) (1)

Sin Nombre Virus (1)

HCoV-OC43 (1)

Staphylococcus aureus (3)

Tick-borne encephalitis virus (1)

HIV-1 (1)

E. coli (1)

Human cytomegalovirus (HCMV/HHV-5) (1)

Dengue Virus type 2 (DENV-2) (1)

Heartland Virus (HRTV) (1)

HCoV-NL63 (1)

Streptococcus equisimilis (1)

Human T-cell leukemia virus 1 (HTLV-1) (2)

Ophiophagus hannah (1)

Rabies virus (RABV) (6)

Chikungunya virus (1)

Monkeypox virus (MPXV) (12)

Corynephage omega (3)

Human metapneumovirus (HMPV) (1)

MERS-CoV (2)

Rat (5)

Dengue Virus type 3 (DENV-3) (1)

Rabbit hemorrhagic disease virus (RHDV) GI.2 (1)

Human astrovirus-2 (1)

Poliovirus type 1 (PV1) (1)

Hepatitis E virus/HEV (3)

Murine norovirus 1 (MNV) (1)

Pig (1)

Hepatitis E virus (2)
Host species

0 selected

Mouse (215)

Human (462)

Rat (10)

Rabbit (2)

Alpaca (23)

Dog (8)

Cat (1)
Clonality

0 selected

Monoclonal (726)
Conjugate

0 selected

Unconjugated (726)