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InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009) (VK805010)

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InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009)

InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009)

InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009)

InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009)

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Spec:

100ug
1mg

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References
Datasheet

Overview

Catalog No.	VK805010
Description	InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009) [CR3009] (VK805010) is a human monoclonal antibody detecting Nucleoprotein in ELISA, FCM, IF, Neutralization. Suitable for SARS-CoV-2. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	SARS-CoV-2
Applications	ELISA, FCM, IF, Neutralization
Host species	Human
Isotype	IgG1, kappa
Clone ID	CR3009
Clonality	Monoclonal
Target	Nucleoprotein, N, Nucleocapsid protein, NC, Protein N, N Protein, SARS-CoV-2
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P0DTC9
RRID	InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009) (abinScience Cat# VK805010, RRID:AB_3729560)
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Nucleoprotein (NP) is a ~45 kDa protein. Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Attenuates the stress granules formation by reducing host G3BP1 access to host mRNAs under stress conditions. 1. Dinesh, DC. et al. (2020) PLoS pathogens 16, e1009100. PMID: 33264373 2. Nabeel-Shah, S. et al. (2022) iScience 25, 103562. PMID: 34901782 3. Dolliver, SM. et al. (2022) PLoS pathogens 18, e1011041. PMID: 36534661
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

Western blot

Western blot analysis was performed using anti-nucleoprotein monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant SARS-CoV-2 nucleoprotein (Catalog No: VK805011)
Lane 2: negative control
Bioactivity

Detects recombinant SARS-CoV-2 nucleoprotein (Catalog No: VK805011) in indirect ELISA

References

Datasheet

InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009).pdf

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InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009)