



| Catalog No. | VK562030 |
|---|---|
| Description |
InVivoMAb Anti-HRSV G/Major surface glycoprotein G Antibody (3G12) [3G12] (VK562030) is a human monoclonal antibody detecting Major surface glycoprotein G in ELISA, Neutralization, WB.
Highlights
|
| Species reactivity | Human respiratory syncytial virus A (strain A2) |
| Applications | ELISA, Neutralization, WB |
| Host species | Human |
| Isotype | IgG1, kappa |
| Clone ID | 3G12 |
| Clonality | Monoclonal |
| Target | Major surface glycoprotein G, Attachment glycoprotein G, Membrane-bound glycoprotein, mG, Mature secreted glycoprotein G, Mature sG, G |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P03423 |
| RRID | InVivoMAb Anti-HRSV G/Major surface glycoprotein G Antibody (3G12) (abinScience Cat# VK562030, RRID:AB_3727049) |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | Major surface glycoprotein G is a ~32 kDa protein. Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (Probable). 1. Feldman, SA. et al. (1999) Journal of virology 73, 6610-7. PMID: 10400758 2. Feldman, SA. et al. (2000) Journal of virology 74, 6442-7. PMID: 10864656 3. Levine, S. et al. (1987) The Journal of general virology 68 ( Pt 9), 2521-4. PMID: 3655746 4. Tripp, RA. et al. (2001) Nature immunology 2, 732-8. PMID: 11477410 5. Jeong, KI. et al. (2015) PloS one 10, e0130517. PMID: 26107373 6. Johnson, SM. et al. (2015) PLoS pathogens 11, e1005318. PMID: 26658574 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for InVivoMAb Anti-HRSV G/Major surface glycoprotein G Antibody (3G12)

Detects recombinant HRSV G/Major surface glycoprotein G (Catalog No: VK562011) in indirect ELISA




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