| Catalog No. | VK425011 |
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| Expression system | Mammalian Cells |
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| Accession | Q8JUX5 |
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| Protein length | Tyr810-Lys1221 |
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| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
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| Species | Chikungunya virus (strain S27-African prototype) (CHIKV) |
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| Nature | Recombinant |
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| Endotoxin level | Please contact with the lab for this information. |
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| Purity | >90% as determined by SDS-PAGE. |
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| Predicted molecular weight | 73.11 kDa |
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| Form | Lyophilized |
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| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
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| Reconstitution | Reconstitute in sterile water for a stock solution. |
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| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt. |
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| Alternate Names | Structural polyprotein, p130, Capsid protein, 3.4.21.90, Coat protein, C, Precursor of protein E3/E2, p62, pE2, Assembly protein E3, Spike glycoprotein E2, E2 envelope glycoprotein, 6K protein, Spike glycoprotein E1, E1 envelope glycoprotein |
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| Background | Chikungunya virus (CHIKV) is a mosquito-borne alphavirus responsible for Chikungunya fever, a disease marked by fever, rash, and joint pain. The E1 envelope glycoprotein, a 47 kDa class II fusion protein, plays a critical role in viral entry by mediating low pH-triggered membrane fusion within host endosomes. It forms heterodimers with E2 glycoproteins, assembling into spike trimers on the viral surface that facilitate host cell attachment and infection. Due to its essential function in viral infectivity, the E1 protein is widely used in studies of viral entry, antibody development, vaccine design, and diagnostic assay optimization. |
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| Note | For research use only. |
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