Anti-HPV16 E7/Protein E7 Antibody (Nb4) (VK556033)

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50ug
100ug
1mg

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Datasheet

Overview

Catalog No.

VK556033

Description

Anti-HPV16 E7/Protein E7 Antibody (Nb4) [Nb4] (VK556033) is a mouse monoclonal antibody detecting Protein E7 in ELISA, Neutralization, WB.

Highlights

●Multi-Application — Validated across multiple applications.

Species reactivity

Human papillomavirus type 16

Applications

ELISA, Neutralization, WB

Host species

Mouse

Isotype

VHH-mFC

Clone ID

Nb4

Clonality

Monoclonal

Target

E7, Protein E7

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03129

RRID

Anti-HPV16 E7/Protein E7 Antibody (Nb4) (abinScience Cat# VK556033, RRID:AB_3725276)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Protein E7 is a ~11 kDa protein. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.

Note

For research use only.

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