Home > Products > Antibodies > Biosimilars

Anti-Human Dkk-1 Reference Antibody (Bhq880, RUO) (HF914026)

Datasheet Share product Copy info

Anti-Human Dkk-1 Reference Antibody (Bhq880, RUO)

Anti-Human Dkk-1 Reference Antibody (Bhq880, RUO)

Price(USD): $

Spec:

100ug
1mg

Number:

Contact us

Overview
Images
References
Datasheet

Overview

Catalog No.	HF914026
Description	BHQ880 (HF914026) is a research-grade recombinant antibody targeting Dickkopf-1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1, kappa
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	Dickkopf-1, SK, hDkk-1, Dkk-1, Dickkopf-related protein 1, DKK1
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	O94907
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	BHQ880, BHQ-880, BHQ880
Background	Dickkopf-related protein 1 (DKK1) is a ~28 kDa protein. Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity. 1. Ahn, VE. et al. (2011) Developmental cell 21, 862-73. PMID: 22000856 2. Niehrs, C. (2006) Oncogene 25, 7469-81. PMID: 17143291
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for Research Grade BHQ880

References

HF914026-SDS-PAGE-1.jpg

Datasheet

Anti-Human Dkk-1 Reference Antibody (Bhq880, RUO).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

=

Concentration

×

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

×

V₁ (Stock Vol.)

=

Working Solution

C₂ (Working Conc.)

×

V₂ (Working Vol.)

Recommendation

Contact us for custom quotes, bulk requests and any other issues.

Mail: support@abinScience.com

Distributor list

Anti-Human Dkk-1 Reference Antibody (Bhq880, RUO)