Anti-Rabies virus Phosphoprotein Polyclonal Antibody (VK139014)

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Datasheet

Overview

Catalog No.

VK139014

Description

Anti-Rabies virus Phosphoprotein Polyclonal Antibody (VK139014) is a rabbit polyclonal antibody detecting Phosphoprotein. Suitable for Rabies virus.

Species reactivity

Rabies virus

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Rabies virus Phosphoprotein (Met69-Cys297).

Target

P, Phosphoprotein, Protein M1, Protein P

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P22363

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Phosphoprotein is a ~33 kDa protein. Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body. Inhibits interferon induction pathways by interacting with host TBK1 and preventing the formation of dynamic cytoplasmic condensates that have liquid properties and that are essential for interferon production.

Note

For research use only

Images

References

Datasheet

Anti-Rabies virus Phosphoprotein Polyclonal Antibody.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Rabies virus Phosphoprotein Polyclonal Antibody (VK139014)

Overview

Images

References

Datasheet

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