Anti-Mouse IL24 antibody (SAA2230) (MC472013)

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Datasheet

Overview

Catalog No.

MC472013

Description

Anti-Mouse IL24 antibody (SAA2230) [SAA2230] (MC472013) is a human monoclonal antibody detecting IL24 in ELISA, Blocking. Suitable for Human and Mouse.

Species reactivity

Human, Mouse

Applications

ELISA, Blocking

Host species

Human

Isotype

IgG1, lambda

Clone ID

SAA2230

Clonality

Monoclonal

Target

IL24

Endotoxin level

Please contact with the lab for this information.

Purity

>95% purity as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q925S4

RRID

Anti-Mouse IL24 antibody (SAA2230) (abinScience Cat# MC472013, RRID:AB_3729826)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

Alternate Names

MDA7, MDA-7, ST16, IL-24, Melanoma differentiation-associated gene 7 protein, Suppression of tumorigenicity 16 protein, IL24, Interleukin-24

Background

Interleukin-24 (IL24) is a ~25 kDa protein. Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis. Possesses antiviral functions and induces the type I interferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal.

1. Wang, J. et al. (2020) Cell death & disease 11, 17. PMID: 31907348

2. Davidson, S. et al. (2022) Science immunology 7, eabi6763. PMID: 35148201

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Mouse IL24 antibody (SAA2230)
Bioactivity

Detects recombinant mouse IL24 (Catalog No: MC472012) in indirect ELISA

References

Datasheet

Anti-Mouse IL24 antibody (SAA2230).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse IL24 antibody (SAA2230) (MC472013)

Overview

Images

References

Datasheet

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