Anti-Human MAEA Recombinant Antibody (SAA1700) (HV483013)

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100ug
1mg

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SDS

Overview

Catalog No.

HV483013

Description

Anti-Human MAEA Antibody (SAA1700) [SAA1700] (HV483013) is a mouse monoclonal antibody detecting MAEA in ELISA. Suitable for Human.

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1700

Clonality

Monoclonal

Target

HLC-10, E3 ubiquitin-protein transferase MAEA, Erythroblast macrophage protein, Cell proliferation-inducing gene 5 protein, P44EMLP, MAEA, Human lung cancer oncogene 10 protein, EMP, Macrophage erythroblast attacher

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q7L5Y9

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

E3 ubiquitin-protein transferase MAEA is a ~45 kDa protein. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1. Plays a role in erythroblast enucleation during erythrocyte maturation and in the development of mature macrophages.

1. Lampert, F. et al. (2018) eLife 7. PMID: 29911972

2. Hanspal, M. et al. (1998) Blood 92, 2940-50. PMID: 9763581

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human MAEA Antibody (SAA1700)

References

Datasheet

Anti-Human MAEA Recombinant Antibody (SAA1700).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human MAEA Recombinant Antibody (SAA1700) (HV483013)

Overview

Images

References

Datasheet

SDS

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