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Anti-Hepatitis E virus/HEV RdRp Replicase Antibody (SAA2697) (VK620093)

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Overview
Catalog No.VK620093
Description
Anti-Hepatitis E virus/HEVHEV RdRp Replicase Antibody (SAA2697) [SAA2697] (VK620093) is a human monoclonal antibody detecting RdRp in ELISA.
Species reactivityHepatitis E virus (HEV)
ApplicationsELISA
Host speciesHuman
IsotypeIgG1
Clone IDSAA2697
Clonality Monoclonal
Target RNA-directed RNA polymerase, RdRp
Endotoxin level <10 EU/mg
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q6J8G2
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Non-structural polyprotein pORF1 (RdRp Replicase) is a ~187 kDa protein. Methyltransferase: Displays a capping enzyme activity. This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus. The enzymatic reaction involves a covalent link between 7-methyl-GMP and the methyltransferase, whereas eukaryotic capping enzymes form a covalent complex only with GMP. Methyltransferase catalyzes transfer of a methyl group from S-adenosylmethionine to GTP and GDP to yield m(7)GTP or m(7)GDP. GDP is a better substrate than GTP.

Note For research use only
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Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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