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Research Grade Catumaxomab (HB104066)

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  • 100ug
  • 1mg
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Overview
Catalog No.HB104066
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesMouseHybridRat
IsotypeIgG2a-kappa/IgG2b-lambda
Expression systemMammalian Cells
ClonalityMonoclonal
TargetEpithelial glycoprotein 314, hEGP314, Major gastrointestinal tumor-associated protein GA733-2, EGP314, TACSTD1, Adenocarcinoma-associated antigen, TROP1, EPCAM, Epithelial glycoprotein, KS 1/4 antigen, Tumor-associated calcium signal transducer 1, M4S1, CD326, Ep-CAM, EGP, Epithelial cell adhesion molecule, M1S2, KSA, Cell surface glycoprotein Trop-1, GA733-2, Epithelial cell surface antigen, MIC18, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Concentration1mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP16422 & P07766
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -263°C.
Alternate NamesBispecific,MusmusG2akappa,anti-EPCAM(Ho-3/TP-A-01)/Ratsp.G2blambda,anti-CD3E(26/II/6-1.2),TPBs01,CAS:509077-98-9
BackgroundCatumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors. The Fc region of Catumaxomab region has binding affinity for FcγR1 (CD 64), FcγRIIA (CD 32a), and FcγRIII (CD 16). Catumaxomab can be used for anti-tumor research, especially epithelial cancers.
NoteFor research use only. Not for use in clinical or therapeutic applications.
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