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Research Grade Urelumab (HC336026)

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  • 100ug
  • 1mg
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Overview
Catalog No.HC336026
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesHuman
IsotypeIgG4-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetTumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA
Concentration1.29mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionQ07011
FormLiquid
Storage buffer0.94mM Citricacid,16.7mM Trisodiumcitratedihydrate,6.2% sucrose,pH 6.5,0.01% Tween80
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -162°C.
Alternate NamesBMS-663513,CAS:934823-49-1
BackgroundUrelumab, a fully human, non-ligand binding, CD137 agonist IgG4 monoclonal antibody, enhances T-cell and natural killer-cell antitumor activity, and may enhance cytotoxic activity of Rituximab (HY-P9913). Urelumab can be used for the research of diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and other types of non-Hodgkin lymphoma (NHL).
NoteFor research use only. Not for use in clinical or therapeutic applications.
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  • Bioactivity

    Detects Human CD137/TNFRSF9 in indirect ELISAs.

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