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Research Grade Galiximab (HW630016)

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  • 100ug
  • 1mg
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Overview
Catalog No.HW630016
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesChimeric
IsotypeIgG1-lambda
Expression systemMammalian Cells
ClonalityMonoclonal
TargetCD80, BB1, T-lymphocyte activation antigen CD80, CD28LG, B7, CD28LG1, LAB7, Activation B7-1 antigen, CTLA-4 counter-receptor B7.1
Concentration1mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP33681
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -141°C.
Alternate NamesIDEC-114,CAS:357613-77-5
BackgroundGaliximab (IDEC 114) is a primatized immunoglobulin G1 (IgG1) lambda monoclonal antibody directed against the CD80 antigen and blocks CD80–CD28 binding. Galiximab has variable regions are primatized (cynomologous monkeys), and the constant regions are human. Galiximab can be used in research of B-cell lymphoma.
NoteFor research use only. Not for use in clinical or therapeutic applications.
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  • Bioactivity

    Detects Human CD80/B7-1 in indirect ELISAs.

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