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Research Grade Inclacumab (HB885026)

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  • 1mg
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Overview
Catalog No.HB885026
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesHuman
IsotypeIgG4-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetLeukocyte-endothelial cell adhesion molecule 3, Platelet activation dependent granule-external membrane protein, Granule membrane protein 140, GMP-140, CD62P, SELP, GRMP, PADGEM, CD62 antigen-like family member P, LECAM3, P-selectin, GMRP
Concentration1.68mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP16109
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -125°C.
Alternate NamesLC1004-002,RO4905417,CAS:1256258-86-2
BackgroundInclacumab (Anti-Human selectin P Recombinant Antibody) is a human monoclonal IgG4 antibody selectively targets P-selectin with a Kd value of 9.9 nM. Inclacumab inhibits P-selectin glycoprotein ligand 1 (PSGL-1) mimetic peptide bind with P-selectin with an IC50 value of 1.9 μg/mL and strongly inhibits cell adhesion.
NoteFor research use only. Not for use in clinical or therapeutic applications.
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