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Research Grade Iratumumab (HB038026)

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Spec:
  • 100ug
  • 1mg
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  • References
  • Datasheet
Overview
Catalog No.HB038026
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetCD30L receptor, Ki-1 antigen, CD30, TNFRSF8, D1S166E, Tumor necrosis factor receptor superfamily member 8, Lymphocyte activation antigen CD30
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
AccessionP28908
FormLiquid
Storage buffer0.01M PBS, pH 7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate NamesMDX-060, 640735-09-7
BackgroundIratumumab (MDX-060) a human anti-CD30 IgG1κ monoclonal antibody. Iratumumab inhibits the growth of CD30-expressing tumor cells. Iratumumab can be used for research of Hodgkin's lymphoma (HL) and anaplastic large-cell lymphoma (ALCL).
NoteFor research use only. Not suitable for clinical or therapeutic use.
Images
  • Bioactivity

    Detects CD30/TNFRSF8 in indirect ELISAs.

  • SDS-PAGE

    SDS-PAGE for Research Grade Iratumumab.

  • Flow CytoMetry

    Flow-cytometry using APC anti-human CD30 antibody. Jurkat cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD30 monoclonal antibody (Catalog: HB038026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

  • Flow CytoMetry

    Flow-cytometry using FITC anti-human CD30 antibody. Jurkat cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD30 monoclonal antibody (Catalog: HB038026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

References

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