| Catalog No. | HV989016 |
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| Species reactivity | Human |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Human |
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| Isotype | IgG4-kappa |
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| Expression system | Mammalian Cells |
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| Species | Human |
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| Clonality | Monoclonal |
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| Target | IL20, Cytokine Zcyto10, ZCYTO10, IL-20, Interleukin-20 |
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| Endotoxin level | Please contact with the lab for this information. |
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| Purity | >95% as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | Q9NYY1 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
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| Alternate Names | 15D2, NN-8226, NNC-0109-0012, 1357158-22-5 |
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| Background | Fletikumab (NNC0109-0012) is a monoclonal antibody targeting to IL-20. Fletikumab can be used for inflammation research, such as rheumatoid arthritis.
• Immune responses to injury and their links to eye disease., PMID:34051364
• Regulation and functions of the IL-10 family of cytokines in inflammation and disease., PMID:21166540
• IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling., PMID:37884352
• Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis., PMID:34698806
• Interleukin-20 is involved in dry eye disease and is a potential therapeutic target., PMID:35681232
• The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis., PMID:30319661
• The Interleukin-20 Cytokine Family in Liver Disease., PMID:29892294
• Interleukin-20., PMID:15120648
• Interleukin 24: Signal Transduction Pathways., PMID:37444474
• Interleukin-19 as an Immunoregulatory Cytokine., PMID:32329704
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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