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Research Grade Tibulizumab (HS856106)

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  • 100ug
  • 1mg
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Overview
Catalog No.HS856106
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesHumanized
IsotypeIgG4-kappa-[scFv]2
Expression systemMammalian Cells
SpeciesHuman
ClonalityMonoclonal
TargetCTLA-8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL-17A, IL17A, CTLA8, IL-17, Interleukin-17A, BAFF, ZTNF4, BLYS, Tumor necrosis factor ligand superfamily member 13B, Dendritic cell-derived TNF-like molecule, TALL-1, TNF- and APOL-related leukocyte expressed ligand 1, BLyS, B lymphocyte stimulator, TNFSF13B, CD257, TNFSF20, TALL1, B-cell-activating factor
Endotoxin levelPlease contact with the lab for this information.
Purity>95% as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
AccessionQ16552 & Q9Y275
FormLiquid
Storage buffer0.01M PBS, pH 7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternate NamesBispecific, LY 3090106, LY-3090106, LY3090106, CAS: 1849636-24-3
BackgroundTibulizumab (LY 3090106) is a tetravalent bispecific monoclonal antibody targeting B-cell activating factor (BAFF) and IL-17A with Kd values of 60 pM and 14 pM, respectively. Tibulizumab can be used for autoimmune disease research.
NoteFor research use only. Not suitable for clinical or therapeutic use.
Images
  • SDS-PAGE

    SDS-PAGE for Research Grade Tibulizumab

  • Bioactivity

    Detects Human IL17A in direct ELISAs.

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