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Research Grade Anti-Dog CD152/CTLA4 Antibody (39A11) (CB651026)

Research Grade Anti-Dog CD152/CTLA4 Antibody (39A11)
Research Grade Anti-Dog CD152/CTLA4 Antibody (39A11)
Price(USD): $
Spec:
  • 100ug
  • 1mg
Number:
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  • Datasheet

Overview
Catalog No.CB651026
Description
Anti-Dog CD152/CTLA4 Antibody (39A11) (CB651026) is a research-grade recombinant antibody targeting CD152. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityDog
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesDog
IsotypeIgG2, kappa
Clone ID39A11
Expression system Mammalian Cells
Clonality Monoclonal
Target Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CTLA4
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9XSI1
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Background

Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Research Grade Anti-Dog CD152/CTLA4 Antibody (39A11)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Dog CD152/CTLA4 Antibody (39A11)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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