| Catalog No. | HY127016 |
|---|
| Species reactivity | Human |
|---|
| Applications | Research Grade Biosimilar |
|---|
| Host species | Human |
|---|
| Isotype | Fusion - [ALPL (alkaline phosphatase, TNSALP, tissue non-specific alkaline phosphatase) 18-502]2 - IGHG1 Fc (Fragment constant) - Asp-Ile-deca-aspartate |
|---|
| Expression system | Mammalian Cells |
|---|
| Target | Alkaline phosphatase liver/bone/kidney isozyme, AP-TNAP, TNSALP, Alkaline phosphatase, tissue-nonspecific isozyme, ALPL |
|---|
| Concentration | 0.5mg/ml |
|---|
| Endotoxin level | Please contact the lab for this information. |
|---|
| Purity | >95% purity as determined by SDS-PAGE. |
|---|
| Purification | Protein A/G, purified from cell culture supernatant. |
|---|
| Accession | P05186 |
|---|
| Form | Liquid |
|---|
| Storage buffer | 0.01M PBS,pH7.4. |
|---|
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -1473°C. |
|---|
| Alternate Names | ENB-0040,STRENSIQ™ |
|---|
| Background | Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2?/? knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP). |
|---|
| Note | For research use only. Not for use in clinical or therapeutic applications. |
|---|
