| Catalog No. | VK617046 |
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| Species reactivity | Human immunodeficiency virus 1 (HIV-1) |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Humanized |
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| Isotype | IgG1-kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | gp120/Glycoprotein 120 |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | Q03805 |
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| Form | Liquid |
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| Storage buffer | 30 mM Histidine, pH5.8, 10% sucrose, 0.02% Tween80 |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | 3BNC117-LS, GS-54232417213-72-8 |
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| Background | Lafuvitug (3BNC-117) is a fully human IgG1 antibody that targets envelope glycoprotein gp120 protein. The isotype control for Lafuvitug can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
• Dual engineered gold nanoparticle based synergistic prophylaxis delivery system for HIV/AIDS., PMID:33799160
• HIV gp120 glycoprotein stimulates the inducible isoform of no synthase in human cultured astrocytoma cells., PMID:7687436
• Human immunodeficiency virus gp120 glycoprotein detected by a monoclonal antibody to a synthetic peptide., PMID:3023102
• Free Energy Perturbation Calculation of Relative Binding Free Energy between Broadly Neutralizing Antibodies and the gp120 Glycoprotein of HIV-1., PMID:27908641
• Dextran sulfate and other polyanionic anti-HIV compounds specifically interact with the viral gp120 glycoprotein expressed by T-cells persistently infected with HIV-1., PMID:1691563
• Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase., PMID:15509740
• Selection and characterization of an HIV-1 gp120-binding affibody ligand., PMID:16712522
• The antiviral lectin cyanovirin-N: probing multivalency and glycan recognition through experimental and computational approaches., PMID:24059504
• Cellular origin of the Bufo arenarum sperm receptor gp75, a ZP2 family member: its proteolysis after fertilization., PMID:17973629
• Sperm head agglutination induced by V3 peptide does not occur through a CD4 receptor., PMID:9509688
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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