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Research Grade Actoxumab (JN085016)

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  • 1mg
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Overview
Catalog No.JN085016
Species reactivityClostridioidesdifficile
ApplicationsResearch Grade Biosimilar
Host speciesHuman
IsotypeIgG1-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetToxin A/tcdA
Concentration1mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP16154
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -1441°C.
Alternate NamesCDA1,MBL-CDA1,MDX-066,MK-3415A(combinationofactoxumabandbezlotoxumab),CAS:1245634-25-6
BackgroundActoxumab (Anti-C. difficile Toxin A Recombinant Antibody) is a antitoxin antibody against C. difficile toxin A by neutralizing TcdA. Actoxumab prevents both the damage to the gut wall and the inflammatory response, which are associated with C. difficile. Actoxumab has synergy effect with Bezlotoxumab (HY-P9929) targeting TcdB.
NoteFor research use only. Not for use in clinical or therapeutic applications.
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