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Research Grade Magrolimab (HC359016)

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  • 100ug
  • 1mg
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Overview
Catalog No.HC359016
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesHumanized
IsotypeIgG4-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetLeukocyte surface antigen CD47, CD47, Antigenic surface determinant protein OA3, IAP, Integrin-associated protein, Protein MER6, MER6
Concentration3.65mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionQ08722
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -1429°C.
Alternate NamesCD47,Hu5F9-G4,CAS:2169232-81-7
BackgroundMagrolimab (Hu5F9-G4) is a humanized anti-CD47 antibody. Magrolimab can block the "don't eat me" signal of CD47, thereby promoting macrophage mediated phagocytosis. Magrolimab has antitumor activity in malignant bone tumors and breast cancer.
NoteFor research use only. Not for use in clinical or therapeutic applications.
Images
  • Bioactivity

    Detects Human CD47/MER6 in indirect ELISAs.

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