| Catalog No. | HP458026 |
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| Species reactivity | Human |
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| Applications | Research Grade Biosimilar |
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| Host species | Human |
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| Isotype | IgG1-lambda/kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | GPRC5D, G-protein coupled receptor family C group 5 member D, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G, purified from cell culture supernatant. |
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| Accession | Q9NZD1 & P07766 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS,pH7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | rg6234,CAS:2649379-96-2 |
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| Background | Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2 + 1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control (HY-P99001). |
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| Note | For research use only. Not for use in clinical or therapeutic applications. |
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