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Research Grade Rilonacept (HF943036)

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  • 100ug
  • 1mg
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Overview
Catalog No.HF943036
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesHuman
IsotypeFusion - [IL1RAP (interleukin-1 receptor accessory protein) - IL1R1 (type 1 interleukin-1 receptor, interleukin 1 receptor, type I)]2 - IGHG1 Fc (Fragment constant)
Expression systemMammalian Cells
TargetInterleukin-1 beta, IL1B, Catabolin, IL1F2, IL-1 beta
Concentration1.72mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP01584
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -1216°C.
Alternate NamesCAS:501081-76-1
BackgroundRilonacept (Arcalyst), a dimeric fusion protein, is a interleukin 1 inhibitor. Rilonacept consists of the ligand-binding domains of the extracellular portions of the IL-1R components linked to the Fc portion of human IgG1. Rilonacept can be used for the research of cryopyrin-associated periodic syndromes.
NoteFor research use only. Not for use in clinical or therapeutic applications.
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  • Bioactivity

    Detects IL1B/IL1F2 in indirect ELISAs.

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