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Research Grade Caplacizumab (HY255016)

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  • 1mg
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Overview
Catalog No.HY255016
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesHumanized
IsotypeVH-VH
Expression systemMammalian Cells
ClonalityMonoclonal
Targetvon Willebrand antigen II, von Willebrand factor, F8VWF, vWF, VWF
Concentration1.6mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP04275
FormLiquid
Storage buffer20mM citric acid,6.2% sucrose,0.01% Tween80
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -606°C.
Alternate NamesALX-0081,PMP12A2h1-linkerAAA-PMP12A2h1,caplacizumab-yhdp,CAS:915810-67-2
BackgroundCaplacizumab (ALX-0681) is a humanized anti-von Willebrand factor (vWF) nanobody. Caplacizumab inhibits the vWF-mediated platelet adhesion and prevents further microthrombi formation. Caplacizumab can be used for the research of thrombotic thrombocytopenic purpura (TTP).
NoteFor research use only. Not for use in clinical or therapeutic applications.
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