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Research Grade Nirsevimab (VK421026)

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  • 100ug
  • 1mg
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Overview
Catalog No.VK421026
Species reactivityHRSV-A
ApplicationsResearch Grade Biosimilar
Host speciesHumanized
IsotypeIgG1, kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetF, Fusion glycoprotein F0, Fusion glycoprotein F2, p27, Intervening segment, Pep27, Peptide 27, Fusion glycoprotein F1
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP03420
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate NamesMEDI-8897,MEDI8897,CAS:1989556-22-0
BackgroundNirsevimab (MEDI8897) is a recombinant monoclonal antibody against human respiratory syncytial virus (RSV). Nirsevimab has neutralizing activity against RSV A and RSV B viruses, with IC50 values of 5.42 ng/mL and 9.71 ng/mL, respectively. Nirsevimab can be used for research on respiratory infections.
NoteFor research use only. Not for use in clinical or therapeutic applications.
Images
  • SDS-PAGE

    SDS-PAGE for Research Grade Nirsevimab

  • SEC-HPLC

    SEC-HPLC detection for Research Grade Nirsevimab.

  • Bioactivity

    Detects Human F/Fusion glycoprotein F0 in indirect ELISAs.

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