Catalog No. | VK421026 |
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Species reactivity | HRSV-A |
Applications | Research Grade Biosimilar |
Host species | Humanized |
Isotype | IgG1, kappa |
Expression system | Mammalian Cells |
Clonality | Monoclonal |
Target | F, Fusion glycoprotein F0, Fusion glycoprotein F2, p27, Intervening segment, Pep27, Peptide 27, Fusion glycoprotein F1 |
Concentration | 3.67mg/ml |
Endotoxin level | Please contact the lab for this information. |
Purity | >95% purity as determined by SDS-PAGE. |
Purification | Protein A/G, purified from cell culture supernatant. |
Accession | P03420 |
Form | Liquid |
Storage buffer | 0.01M PBS,pH7.4. |
Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -490°C. |
Alternate Names | MEDI-8897,MEDI8897,CAS:1989556-22-0 |
Background | Nirsevimab (MEDI8897) is a recombinant monoclonal antibody against human respiratory syncytial virus (RSV). Nirsevimab has neutralizing activity against RSV A and RSV B viruses, with IC50 values of 5.42 ng/mL and 9.71 ng/mL, respectively. Nirsevimab can be used for research on respiratory infections. |
Note | For research use only. Not for use in clinical or therapeutic applications. |
SDS-PAGE for Research Grade Nirsevimab
SEC-HPLC detection for Research Grade Nirsevimab.
Detects Human F/Fusion glycoprotein F0 in indirect ELISAs.
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