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Research Grade Nirsevimab (VK421026)

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  • 100ug
  • 1mg
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Overview
Catalog No.VK421026
Species reactivityHRSV-A
ApplicationsResearch Grade Biosimilar
Host speciesHumanized
IsotypeIgG1, kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetF, Fusion glycoprotein F0, Fusion glycoprotein F2, p27, Intervening segment, Pep27, Peptide 27, Fusion glycoprotein F1
Concentration3.67mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP03420
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -490°C.
Alternate NamesMEDI-8897,MEDI8897,CAS:1989556-22-0
BackgroundNirsevimab (MEDI8897) is a recombinant monoclonal antibody against human respiratory syncytial virus (RSV). Nirsevimab has neutralizing activity against RSV A and RSV B viruses, with IC50 values of 5.42 ng/mL and 9.71 ng/mL, respectively. Nirsevimab can be used for research on respiratory infections.
NoteFor research use only. Not for use in clinical or therapeutic applications.
Images
  • SDS-PAGE

    SDS-PAGE for Research Grade Nirsevimab

  • SEC-HPLC

    SEC-HPLC detection for Research Grade Nirsevimab.

  • Bioactivity

    Detects Human F/Fusion glycoprotein F0 in indirect ELISAs.

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