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Research Grade Suvizumab (VK617016)

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  • 100ug
  • 1mg
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Overview
Catalog No.VK617016
Species reactivityHumanimmunodeficiencyvirus1(HIV-1)
ApplicationsResearch Grade Biosimilar
Host speciesHumanized
IsotypeIgG1, kappa
Expression systemMammalian Cells
ClonalityMonoclonal
Targetenv/Env polyprotein
Concentration1mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP03377
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -482°C.
Alternate NamesKD-247,CAS:914257-21-9
BackgroundSuvizumab (KD-247) is an neutralizing antibody anti-HIV-1. Suvizumab effectively neutralizes HIV-1MN, HIV-1SF2 and HIV-189.6 with IC50 values of 0.1 µg/mL, 1.0 µg/mL and 0.2 µg/mL, respectively. Suvizumab reduces the viral load of HIV. Suvizumab has good tolerance and can be used to prevent HIV infection.
NoteFor research use only. Not for use in clinical or therapeutic applications.
Images
  • SEC-HPLC

    SEC-HPLC detection for Research Grade Suvizumab.

  • Bioactivity

    Detects env/Env polyprotein in indirect ELISAs.

References

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