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Research Grade Sotrovimab (VK565076)

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  • 100ug
  • 1mg
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Overview
Catalog No.VK565076
Species reactivitySARS-CoV-2(2019-nCoV)
ApplicationsResearch Grade Biosimilar
Host speciesHuman
IsotypeIgG1, kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetSpike glycoprotein, S glycoprotein, E2, Peplomer protein, Spike protein S1, Spike protein S2, Spike protein S2', S, 2
Concentration3.03mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP0DTC2
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -474°C.
Alternate NamesVIR-7831,GSK4182136,S309,CAS:2423014-07-5
BackgroundSotrovimab (VIR 7831) is a human IgG1κ pan-sarbecovirus monoclonal antibody (mAb), neutralizes SARS-CoV-2, SARS-CoV-1, and multiple other sarbecoviruses. Sotrovimab is developed based on S309, exhibits a long half-life and great bioavailability in the respiratory mucosa. Sotrovimab could result in immune-mediated viral clearance and prevent progression of Covid-19 early in the course of disease.
NoteFor research use only. Not for use in clinical or therapeutic applications.
Images
  • SDS-PAGE

    SDS-PAGE for Research Grade Sotrovimab

  • Bioactivity

    Detects RBD in indirect ELISAs.

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