| Catalog No. | JN969016 |
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| Species reactivity | Staphylococcus aureus |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Human |
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| Isotype | IgG1-kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | lukG |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | A0A6B5MC52 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | ASN-100(combinationofatidortoxumabandberlimatoxumab), ASN-2, 1939109-24-6 |
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| Background | Berlimatoxumab (ASN-2) is an antibody. Berlimatoxumab can be used for experiment research.
• Separately or combined, LukG/LukH is functionally unique compared to other staphylococcal bicomponent leukotoxins., PMID:24586678
• Molecular mechanism of leukocidin GH-integrin CD11b/CD18 recognition and species specificity., PMID:31852826
• Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies., PMID:27467113
• Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH., PMID:25371205
• Adaptive laboratory evolution and independent component analysis disentangle complex vancomycin adaptation trajectories., PMID:35858453
• Human antibody responses against non-covalently cell wall-bound Staphylococcus aureus proteins., PMID:29459694
• Identification of a novel Staphylococcus aureus two-component leukotoxin using cell surface proteomics., PMID:20661294
• Serum neutralizing antibody after rabies postexposure prophylaxis., PMID:945973
• Pancreatic Enzyme Replacement Therapy Use in Infants With Cystic Fibrosis Diagnosed by Newborn Screening., PMID:29176494
• Vitamin E regulates mitochondrial hydrogen peroxide generation., PMID:10490278
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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