| Catalog No. | HW651016 |
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| Species reactivity | Human |
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| Applications | Research Grade Biosimilar |
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| Host species | Human |
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| Isotype | IgG2-kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | Serine/threonine-protein kinase receptor R3, ACVRL1, Activin receptor-like kinase 1, ALK-1, ACVRLK1, ALK1, SKR3, TGF-B superfamily receptor type I, TSR-I |
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| Concentration | 1mg/ml |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G, purified from cell culture supernatant. |
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| Accession | P37023 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS,pH7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -431°C. |
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| Alternate Names | PF-03446962,CAS:1463459-96-2 |
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| Background | Ascrinvacumab (PF-03446962) is a human IgG2 monoclonal antibody targets ALK-1. Ascrinvacumab shows binding efficiency with human ALK1 with a Kd value of 7 nM. Ascrinvacumab can be used for the research of hepatocellular carcinoma (HCC). |
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| Note | For research use only. Not for use in clinical or therapeutic applications. |
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