| Catalog No. | HB801016 |
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| Species reactivity | Human |
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| Applications | Research Grade Biosimilar |
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| Host species | Chimeric |
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| Isotype | IgG1-kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | PRLR, PRL-R, Prolactin receptor |
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| Concentration | 1mg/ml |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G, purified from cell culture supernatant. |
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| Accession | P16471 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS,pH7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -415°C. |
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| Alternate Names | PR-1594804,h16f,ABBV-176,DC-1630993,h16f,Rolinsatamabtalirine,CAS:2095467-30-2 |
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| Background | Rolinsatamab is a IgG1κ type chimeric antibody targeting to PRLR (prolactin receptor). Rolinsatamab can be conjugated with pyrrolobenzodiazepine (PDB) dimer SGD-1882 (HY-101127) via a cleavable maleimidocaproyl type linker, to form an antibody-drug conjugate, Rolinsatamab talirine. One Rolinsatamab talirine has an average of 2 site-specific drug attachment engineered cysteines (S239C). The linker equips the valine-alanine dipeptide, as cathepsine B cleavage site. on an average of 2 site-specific drug attachment engineered cysteines (S239C). |
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| Note | For research use only. Not for use in clinical or therapeutic applications. |
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