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Research Grade Concizumab (HY403026)

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  • 100ug
  • 1mg
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Overview
Catalog No.HY403026
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesHumanized
IsotypeIgG4-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetExtrinsic pathway inhibitor, Lipoprotein-associated coagulation inhibitor, TFPI, EPI, LACI, TFPI1, Tissue factor pathway inhibitor
Concentration0.73mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP10646
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -309°C.
Alternate NamesAnti-TFPI,NN7415,mab2021,CAS:1312299-39-0
BackgroundConcizumab is an anti-TFPI monoclonal antibody (IgG4 type) that binds to the Kunitz-type protease inhibitor (KPI) 2 structural domain of TFPI, thereby blocking the interaction of this structural domain with the FXa active site. Concizumab can be used in the study of haemophilia.
NoteFor research use only. Not for use in clinical or therapeutic applications.
Images
  • SDS-PAGE

    SDS-PAGE for Research Grade Concizumab

  • SEC-HPLC

    SEC-HPLC detection for Research Grade Concizumab.

  • Bioactivity

    Detects TFPI in indirect ELISAs.

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