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Research Grade Abelacimab (HY171026)

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  • 100ug
  • 1mg
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Overview
Catalog No.HY171026
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesHuman
IsotypeIgG1-lambda
Expression systemMammalian Cells
ClonalityMonoclonal
TargetPlasma thromboplastin antecedent, PTA, Coagulation factor XI, F11, FXI
Concentration1.47mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP03951
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -306°C.
Alternate NamesNVS250519,CAS:2098724-83-3,FXI,FXIa,
BackgroundAbelacimab (MAA868) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab can be used in thromboembolic disease studies.
NoteFor research use only. Not for use in clinical or therapeutic applications.
Images
  • SEC-HPLC

    SEC-HPLC detection for Research Grade Abelacimab.

  • Bioactivity

    Detects F11 in indirect ELISAs.

References

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