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Research Grade Depatuxizumab (HF004086)

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  • 100ug
  • 1mg
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Overview
Catalog No.HF004086
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesHumanized
IsotypeIgG1-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetHER1, Receptor tyrosine-protein kinase erbB-1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, EGFR, ERBB1, ERBB
Concentration1mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP00533
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -284°C.
Alternate NamesABT-806,ABT-414,unconjugate:ABT-806,CAS:1471999-69-5
BackgroundDepatuxizumab is a brain-penetrant and humanized tumor-specific anti EGFR monoclonal antibody. Depatuxizumab inhibits the growth of xenograft models of mutant EGFRvIII and wild-type EGFR. Depatuxizumab can be used for research on cancer.
NoteFor research use only. Not for use in clinical or therapeutic applications.
Images
  • SEC-HPLC

    SEC-HPLC detection for Research Grade Depatuxizumab.

  • Bioactivity

    Detects EGFR/ERBB1/HER1 in indirect ELISAs.

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