| Catalog No. | HV029016 |
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| Species reactivity | Human |
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| Applications | Research Grade Biosimilar |
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| Host species | Humanized |
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| Isotype | IgG4-kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | T-cell immunoglobulin mucin receptor 3, HAVcr-2, TIMD-3, T-cell membrane protein 3, HAVCR2, Hepatitis A virus cellular receptor 2, CD366, TIMD3, TIM-3, TIM3, T-cell immunoglobulin and mucin domain-containing protein 3 |
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| Concentration | 1mg/ml |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G, purified from cell culture supernatant. |
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| Accession | Q8TDQ0 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS,pH7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -276°C. |
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| Alternate Names | TSR-022,CAS:2022215-65-0 |
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| Background | Cobolimab (TSR-022) is an anti-TIM-3 monoclonal antibody. Cobolimab mediates the internalization of TIM3 with an IC50 value of 0.4464 nM. Cobolimab has potential application in solid tumors and non-small cell lung cancer (NSCLC). |
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| Note | For research use only. Not for use in clinical or therapeutic applications. |
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