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Research Grade Pacmilimab (HV974056)

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Spec:
  • 100ug
  • 1mg
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  • Datasheet
Overview
Catalog No.HV974056
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG4-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetB7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
AccessionQ9NZQ7
FormLiquid
Storage buffer0.01M PBS, pH 7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate NamesCX-072, 2145091-51-4
BackgroundPacmilimab (CX-072) is a potent PD-L1 inhibitor. Pacmilimab shows antitumor activity.
NoteFor research use only. Not suitable for clinical or therapeutic use.
Images
  • SEC-HPLC

    SEC-HPLC detection for Research Grade Pacmilimab.

  • Bioactivity

    Detects Human CD274/PD-L1/B7-H1 in indirect ELISAs.

  • SDS-PAGE

    SDS-PAGE for Research Grade Pacmilimab.

  • Flow CytoMetry

    Flow-cytometry using anti-human CD274 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD274 monoclonal antibody (Catalog: HV974056) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

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