| Catalog No. | HV375016 |
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| Species reactivity | Human |
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| Applications | Research Grade Biosimilar |
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| Host species | Chimeric |
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| Isotype | IgG4-kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | B- and T-lymphocyte attenuator, BTLA, CD272, B- and T-lymphocyte-associated protein |
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| Concentration | 2.61mg/ml |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G, purified from cell culture supernatant. |
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| Accession | Q7Z6A9 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS,pH7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -222°C. |
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| Alternate Names | JS004,Icatolimab,CAS:2236068-83-8 |
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| Background | Tifcemalimab (JS004) is a humanized anti-BTLA (B and T lymphocyte attenuation factor) monoclonal antibody. Tifcemalimab blocks the interaction of HVEM-BTLA by binding to BTLA, and thus blocks the inhibitory signaling pathway mediated by BTLA. Tifcemalimab can be used in research of cancer. |
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| Note | For research use only. Not for use in clinical or therapeutic applications. |
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