









| Каталожный номер | HV599016 |
|---|---|
| Описание |
Ianalumab (HV599016) is a research-grade recombinant antibody targeting CD268. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Реактивность видов | Human |
| Применения | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Хозяинский вид | Human |
| Изотип | IgG1-kappa |
| Система экспрессии | Mammalian Cells |
| Клоональность | Monoclonal |
| Цель | BR3, TNFRSF13C, BAFF receptor, BLyS receptor 3, Tumor necrosis factor receptor superfamily member 13C, CD268, B-cell-activating factor receptor, BAFFR, BAFF-R |
| Уровень эндотоксинов | Please contact the lab for this information. |
| Чистота | >95% purity as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q96RJ3 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS, pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Альтернативные названия | VAY-736, 1929549-92-7 |
| Фон | Tumor necrosis factor receptor superfamily member 13C (CD268/TNFRSF13C) is a ~18 kDa protein. B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |

SEC-HPLC detection for Research Grade Ianalumab.

Detects CD268/TNFRSF13C in indirect ELISAs.

SDS-PAGE for Research Grade Ianalumab

Flow cytometry using Ianalumab-APC. Untransfected BAFFR-negative cells (blue histogram) and human BAFFR-stable transfected cells (yellow histogram) were incubated with APC-labeled Ianalumab (5 µg/ml) for 30 minutes at room temperature. After washing, cells were analyzed on a NovoCyte Flow Cytometer.

Flow cytometry using Ianalumab-APC. Untransfected BAFFR-negative cells (blue histogram) and mouse BAFFR-stable transfected cells (yellow histogram) were incubated with APC-labeled Ianalumab (5 µg/ml) for 30 minutes at room temperature. After washing, cells were analyzed on a NovoCyte Flow Cytometer.




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