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Research Grade Conatumumab (HT348036)

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  • 100ug
  • 1mg
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Overview
Catalog No.HT348036
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesHuman
IsotypeIgG1-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetTRAILR2, TRAIL-R2, Death receptor 5, CD262, DR5, Tumor necrosis factor receptor superfamily member 10B, ZTNFR9, TRAIL receptor 2, TRICK2, TNFRSF10B, KILLER, TNF-related apoptosis-inducing ligand receptor 2
Concentration2.89mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionO14763
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -215°C.
Alternate NamesAMG655,TRAIL-R2mAb,XG1-048vw,CAS:896731-82-1
BackgroundConatumumab (AMG 655) is a human monoclonal agonist antibody against human death receptor 5 (DR5, TRAILR2) (Kd: 1 nM for the long form of DR5, 0.8 nM for the short form of DR5). Conatumumab induces apoptosis via caspase activation. Conatumumab can be used in the research of cancers. .
NoteFor research use only. Not for use in clinical or therapeutic applications.
Images
  • Bioactivity

    Detects CD262/TNFRSF10B/TRAIL-R2/DR5 in indirect ELISAs.

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