

| Каталожный номер | HV217010 |
|---|---|
| Описание |
InVivoMAb Anti-Human CD319/SLAMF7 Antibody (Iv0264) [Iv0264] (HV217010) is a human monoclonal antibody detecting SLAMF7 in ELISA, Neutralization, WB. Suitable for Human.
Highlights
|
| Реактивность видов | Human |
| Применения | ELISA, Neutralization, WB |
| Хозяинский вид | Human |
| Изотип | IgG1, kappa |
| ID клона | Iv0264 |
| Клоональность | Monoclonal |
| Цель | SLAMF7, CRACC, Protein 19A, SLAM family member 7, CD2-like receptor-activating cytotoxic cells, Membrane protein FOAP-12, CD319, Novel Ly9, CD2 subset 1, CS1 |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q9NQ25 |
| RRID | InVivoMAb Anti-Human CD319/SLAMF7 Antibody (Iv0264) (abinScience Cat# HV217010, RRID:AB_3729619) |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS, pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Фон | SLAM family member 7 (CD319/SLAMF7) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. 1. Bouchon, A. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 5517-21. PMID: 11698418 2. Tassi, I. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7996-8002. PMID: 16339536 3. Murphy, JJ. et al. (2002) The Biochemical journal 361, 431-6. PMID: 11802771 4. Kim, JR. et al. (2013) Inflammation research : official journal of the European Histamine Research Society ... [et al.] 62, 765-72. PMID: 23695528 |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for InVivoMAb Anti-Human CD319/SLAMF7 Antibody (Iv0264)




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