-abinscience.jpg)

-abinscience.jpg)

| Каталожный номер | VK565120 |
|---|---|
| Описание |
InVivoMAb Anti-SARS-CoV-2 RBD (JN.1) Neutralizing Antibody (Iv0222) [Iv0222] (VK565120) is a human monoclonal antibody detecting Spike glycoprotein in ELISA, Neutralization.
|
| Реактивность видов | SARS-CoV-2 (2019-nCoV) |
| Применения | ELISA, Neutralization |
| Хозяинский вид | Human |
| Изотип | IgG1, kappa |
| ID клона | Iv0222 |
| Клоональность | Monoclonal |
| Цель | Spike glycoprotein, S glycoprotein, Spike protein S1, Receptor-Binding Domain, RBD, JN.1, SARS-CoV-2 (2019-nCoV) |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | P0DTC2 |
| RRID | InVivoMAb Anti-SARS-CoV-2 RBD (JN.1) Neutralizing Antibody (Iv0222) (abinScience Cat# VK565120, RRID:AB_3729381) |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS, pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Фон | Spike glycoprotein (RBD (Omicron/JN.1)) is a ~141 kDa protein. Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2. When S2/S2' has been cleaved, binding to the receptor triggers direct fusion at the cell membrane. When S2/S2' has not been cleaved, binding to the receptor results in internalization of the virus by endocytosis using host TFRC and GRM2 and leading to fusion of the virion membrane with the host endosomal membrane. Alternatively, may use NRP1/NRP2 and integrin as entry receptors. 1. Hoffmann, M. et al. (2020) Cell 181, 271-280.e8. PMID: 32142651 2. Walls, AC. et al. (2020) Cell 181, 281-292.e6. PMID: 32155444 3. Cao, W. et al. (2021) Biophysical journal 120, 1011-1019. PMID: 33607086 4. Takeda, M. (2022) Microbiology and immunology 66, 15-23. PMID: 34561887 5. Wrapp, D. et al. (2020) Science (New York, N.Y.) 367, 1260-1263. PMID: 32075877 6. Ou, X. et al. (2020) Nature communications 11, 1620. PMID: 32221306 7. Wang, J. et al. (2021) Cell discovery 7, 119. PMID: 34903715 8. Wang, X. et al. (2023) Journal of virology 97, e0161122. PMID: 36779763 9. Daly, JL. et al. (2020) Science (New York, N.Y.) 370, 861-865. PMID: 33082294 10. Cantuti-Castelvetri, L. et al. (2020) Science (New York, N.Y.) 370, 856-860. PMID: 33082293 |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |
-abinscience.jpg)
Detects SARS-CoV-2 RBD(JN.1) in indirect ELISAs.

SDS-PAGE for InVivoMAb Anti-SARS-CoV-2 RBD (JN.1) Neutralizing Antibody (Iv0222).




Свяжитесь с нами для индивидуальных предложений, оптовых запросов и других вопросов.
Почта: support@abinScience.com
-abinscience.jpg)

-abinscience.jpg)

+86-027-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский