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InVivoMAb Anti-SARS-CoV-2 RBD Antibody (S309)
InVivoMAb Anti-SARS-CoV-2 RBD Antibody (S309)
InVivoMAb Anti-SARS-CoV-2 RBD Antibody (S309)
InVivoMAb Anti-SARS-CoV-2 RBD Antibody (S309)
InVivoMAb Anti-SARS-CoV-2 RBD Antibody (S309)
InVivoMAb Anti-SARS-CoV-2 RBD Antibody (S309)
Цена(USD): $
Спецификация:
  • 100ug
  • 1mg
Количество:
Свяжитесь с нами
  • Обзор

  • Изображения

  • Ссылки

  • Даташит

Обзор
Каталожный номерVK565010
Описание
InVivoMAb Anti-SARS-CoV-2 RBD Antibody (S309) [S309] (VK565010) is a human monoclonal antibody detecting Spike glycoprotein in ELISA, Neutralization. Suitable for SARS-CoV.
Реактивность видовSARS-CoV-2(2019-nCoV), SARS-CoV
ПримененияELISA, Neutralization
Хозяинский видHuman
ИзотипIgG1, kappa
ID клонаS309
Клоональность Monoclonal
Цель Spike glycoprotein, S glycoprotein, E2, Peplomer protein, RBD, Spike protein S1, S, Receptor-Binding Domain
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P0DTC2
RRID InVivoMAb Anti-SARS-CoV-2 RBD Antibody (S309) (abinScience Cat# VK565010, RRID:AB_3727074)
Форма Liquid
Буфер хранения 0.01M PBS, pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон

Spike glycoprotein (RBD) is a ~141 kDa protein. Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2. When S2/S2' has been cleaved, binding to the receptor triggers direct fusion at the cell membrane. When S2/S2' has not been cleaved, binding to the receptor results in internalization of the virus by endocytosis using host TFRC and GRM2 and leading to fusion of the virion membrane with the host endosomal membrane. Alternatively, may use NRP1/NRP2 and integrin as entry receptors.

1. Hoffmann, M. et al. (2020) Cell 181, 271-280.e8. PMID: 32142651
2. Walls, AC. et al. (2020) Cell 181, 281-292.e6. PMID: 32155444
3. Cao, W. et al. (2021) Biophysical journal 120, 1011-1019. PMID: 33607086
4. Takeda, M. (2022) Microbiology and immunology 66, 15-23. PMID: 34561887
5. Wrapp, D. et al. (2020) Science (New York, N.Y.) 367, 1260-1263. PMID: 32075877
6. Ou, X. et al. (2020) Nature communications 11, 1620. PMID: 32221306
7. Wang, J. et al. (2021) Cell discovery 7, 119. PMID: 34903715
8. Wang, X. et al. (2023) Journal of virology 97, e0161122. PMID: 36779763
9. Daly, JL. et al. (2020) Science (New York, N.Y.) 370, 861-865. PMID: 33082294
10. Cantuti-Castelvetri, L. et al. (2020) Science (New York, N.Y.) 370, 856-860. PMID: 33082293
Примечание For research use only. Not suitable for clinical or therapeutic use.
Изображения
  • InVivoMAb Anti-SARS-CoV-2 RBD Antibody (S309)

    Bioactivity

    SEC-HPLC detection for InVivoMAb Anti-SARS-CoV-2 RBD Antibody (S309).

  • InVivoMAb Anti-SARS-CoV-2 RBD Antibody (S309)

    Bioactivity

    Detects SARS-CoV-2 RBD (KP.2 variant) in indirect ELISA.

  • InVivoMAb Anti-SARS-CoV-2 RBD Antibody (S309)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-SARS-CoV-2 RBD Antibody (S309).

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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