Anti-Parainfluenza virus 5/PIV5 Protein P Antibody (SAA0288) (VK443013)

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Overview

Catalog No.

VK443013

Description

Anti-Parainfluenza virus 5/PIV5 Protein P Antibody (SAA0288) [SAA0288] (VK443013) is a mouse monoclonal antibody detecting Protein P in ELISA, Neutralization.

Species reactivity

Parainfluenza virus 5 (PIV5)

Applications

ELISA, Neutralization

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA0288

Clonality

Monoclonal

Target

Phosphoprotein, Protein P, P/V

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P11208

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Phosphoprotein (Protein P) is a ~42 kDa protein. Essential cofactor of the RNA polymerase L that plays a central role in the transcription and replication by forming the polymerase complex with RNA polymerase L and recruiting L to the genomic N-RNA template for RNA synthesis. Also plays a central role in the encapsidation of nascent RNA chains by forming the encapsidation complex with the nucleocapsid protein N (N-P complex). Acts as a chaperone for newly synthesized free N protein, so-called N0, allowing encapsidation of nascent RNA chains during replication. The nucleoprotein protein N prevents excessive phosphorylation of P, which leads to down-regulation of viral transcription/ replication. Participates, together with N, in the formation of viral factories (viroplasms), which are large inclusions in the host cytoplasm where replication takes place.

Note

For research use only.

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