Anti-HCV ssRNA & Genome polyprotein Antibody (Fab HCV3) (VK745013)

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50ug
100ug
1mg

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Datasheet

Overview

Catalog No.

VK745013

Description

Anti-HCV ssRNA & Genome polyprotein Antibody (Fab HCV3) [Fab HCV3] (VK745013) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.

Species reactivity

Hepatitis C virus genotype 1b (isolate BK) (HCV)

Applications

ELISA, Neutralization

Host species

Human

Isotype

IgG1, kappa

Clone ID

Fab HCV3

Clonality

Monoclonal

Target

ssRNA, Genome polyprotein, Single-stranded RNA

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P26663

RRID

Anti-HCV ssRNA & Genome polyprotein Antibody (Fab HCV3) (abinScience Cat# VK745013, RRID:AB_3725321)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Genome polyprotein (ssRNA & Genome polyprotein) is a ~327 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication (Probable). Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable).

Note

For research use only.

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