Anti-HCV Hepacivirin/NS3 helicase/NS3P/Viroporin p70 Antibody (24#) (VK506033)

Datasheet Share product Copy info

Price(USD): $

Spec:

20ug
50ug
100ug
1mg

Number:

Overview
Images
References
Datasheet

Overview

Catalog No.

VK506033

Description

Anti-HCV Hepacivirin/NS3 helicase/NS3P/Viroporin p70 Antibody (24#) [24#] (VK506033) is a human monoclonal antibody detecting Viroporin p70 in ELISA, Neutralization.

Species reactivity

Hepatitis C virus genotype 3a (isolate NZL1) (HCV)

Applications

ELISA, Neutralization

Host species

Human

Isotype

IgG1, kappa

Clone ID

24#

Clonality

Monoclonal

Target

Hepacivirin, NS3 helicase, NS3P, Viroporin p70, Genome polyprotein

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q81258

RRID

Anti-HCV Hepacivirin/NS3 helicase/NS3P/Viroporin p70 Antibody (24#) (abinScience Cat# VK506033, RRID:AB_3725320)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Genome polyprotein (Hepacivirin/NS3P) is a ~329 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable).

1. Jackel-Cram, C. et al. (2007) Journal of hepatology 46, 999-1008. PMID: 17188392

Note

For research use only.

Images