| Catalog No. | DB651018 |
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| Sample type | Plasma, Serum |
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| Sensitivity | 0.156 μg/ml |
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| Range | 0.31-5 μg/mL |
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| Accession | P16410 |
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| Applications | ELISA |
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| Detection method | Colorimetric |
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| Assay type | Quantitative |
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| Recovery | 80-120% |
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| Shipping | 2-8 ℃ |
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| Stability and Storage | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
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| Specifications | Ipilimumab |
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| Alternate Names | BMS-734016, MDX-010, MDX-CTLA-4, CAS: 477202-00-9 |
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| Background | Ipilimumab is a fully human IgG1 kappa antibody that binds to CTLA-4 (cytotoxic T lymphocyte associated antigen 4), a molecule on T cells that is indicated for unresectable or metastatic melanoma. The absence or presence of CTLA-4 can augment or suppress the immune system's T-cell response in fighting disease. Ipilimumab is designed to block the activity of CTLA-4, thereby sustaining an active immune response in its attack on cancer cells. The proposed mechanism of action is indirect, and may be through T-cell - mediated anti-tumor immune responses. |
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| Note | For Research Use Only. |
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