Anti-Human FGF1/aFGF Antibody (SAA0436), PE (HY232127)

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Overview

Catalog No.	HY232127
Description	Anti-Human FGF1/aFGF Antibody (SAA0436), PE [SAA0436] (HY232127) is a mouse monoclonal antibody detecting FGF1 in ELISA, FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0436
Conjugation	PE
Clonality	Monoclonal
Target	Endothelial cell growth factor, HBGF-1, Fibroblast growth factor 1, FGF1, ECGF, Acidic fibroblast growth factor, aFGF, Heparin-binding growth factor 1, FGF-1, FGFA
Endotoxin level	Please contact with the lab for this information.
Accession	P05230
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Fibroblast growth factor 1 (FGF1/aFGF) is a ~17 kDa protein. Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. 1. Mori, S. et al. (2008) The Journal of biological chemistry 283, 18066-75. PMID: 18441324 2. Yamaji, S. et al. (2010) PloS one 5, e10273. PMID: 20422052 3. Mori, S. et al. (2013) PloS one 8, e57927. PMID: 23469107
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human FGF1/aFGF Antibody (SAA0436), PE.pdf

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Anti-Human FGF1/aFGF Antibody (SAA0436), PE (HY232127)

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