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Anti-Human CD49d/ITGA4 Antibody (SAA0019), PerCP (HY596147)

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Overview

Catalog No.	HY596147
Description	Anti-Human CD49d/ITGA4 Antibody (SAA0019), PerCP [SAA0019] (HY596147) is a rabbit monoclonal antibody detecting ITGA4 in ELISA, FCM. Suitable for Human. Highlights ●Rabbit Monoclonal — High specificity, affinity, and excellent lot-to-lot consistency. ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human
Applications	ELISA, FCM
Host species	Rabbit
Isotype	IgG, kappa
Clone ID	SAA0019
Conjugation	PerCP
Clonality	Monoclonal
Target	ITGA4, CD49d, CD49 antigen-like family member D, CD49D, VLA-4 subunit alpha, Integrin alpha-IV, Integrin alpha-4
Endotoxin level	Please contact with the lab for this information.
Accession	P13612
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Integrin alpha-4 (CD49d/ITGA4) is a ~114 kDa protein. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. 1. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415 2. Saegusa, J. et al. (2008) The Journal of biological chemistry 283, 26107-15. PMID: 18635536 3. Fujita, M. et al. (2015) The Journal of biological chemistry 290, 259-71. PMID: 25398877 4. Morris, GE. et al. (2022) British journal of pharmacology 179, 4958-4973. PMID: 35802072
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human CD49d/ITGA4 Antibody (SAA0019), PerCP.pdf

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Anti-Human CD49d/ITGA4 Antibody (SAA0019), PerCP