

| Catalog No. | HF719137 |
|---|---|
| Description |
Anti-Human CD218b/IL18RAP Antibody (3131#), APC [3131#] (HF719137) is a mouse monoclonal antibody detecting IL18RAP in FCM. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | FCM |
| Host species | Mouse |
| Isotype | IgG1, kappa |
| Clone ID | 3131# |
| Conjugation | APC |
| Clonality | Monoclonal |
| Target | AcPL, Accessory protein-like, Interleukin-1 receptor 7, IL-18R-beta, CD218 antigen-like family member B, IL-1RAcPL, Interleukin-18 receptor accessory protein, CDw218b, IL-1R-7, IL1R7, IL-1R7, IL-18RAcP, CD218b, IL-1R accessory protein-like, IL18RAP, Interleukin-18 receptor accessory protein-like, IL-18 receptor accessory protein, IL-18Rbeta, Interleukin-18 receptor beta |
| Endotoxin level | Please contact with the lab for this information. |
| Accession | O95256 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | Interleukin-18 receptor accessory protein (CD218b/IL18RAP) is a ~68 kDa protein. Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable). 1. Kato, Z. et al. (2003) Nature structural biology 10, 966-71. PMID: 14528293 2. Tsutsumi, N. et al. (2014) Nature communications 5, 5340. PMID: 25500532 3. Born, TL. et al. (1998) The Journal of biological chemistry 273, 29445-50. PMID: 9792649 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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